J Ding Selected Research

salvicine

9/2001	Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes.
7/2001	Induction of bulk and c-myc P2 promoter-specific DNA damage by an anti-topoisomerase II agent salvicine is an early event leading to apoptosis in HL-60 cells.
1/2001	Induction of apoptosis in human leukemia K-562 and gastric carcinoma SGC-7901 cells by salvicine, a novel anticancer compound.

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J Ding Research Topics

Disease

41	Neoplasms (Cancer) 10/2023 - 04/2000
8	Necrosis 01/2021 - 04/2000
7	Infections 04/2023 - 10/2000
7	Neoplasm Metastasis (Metastasis) 09/2019 - 09/2004
6	Carcinoma (Carcinomatosis) 10/2023 - 01/2001
6	Leukemia 08/2012 - 08/2000
5	Breast Neoplasms (Breast Cancer) 12/2016 - 11/2006
5	Hepatocellular Carcinoma (Hepatoma) 10/2016 - 02/2006
4	Type 2 Diabetes Mellitus (MODY) 01/2024 - 06/2011
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 09/2001
4	Inflammation (Inflammations) 10/2021 - 04/2000
4	Carcinogenesis 08/2013 - 06/2001
3	Dementia (Dementias) 01/2024 - 08/2008
3	Obesity 01/2024 - 07/2017
3	Hemorrhage 06/2023 - 07/2002
3	Kidney Diseases (Kidney Disease) 01/2023 - 10/2017
3	Strabismus (Squint) 09/2022 - 08/2016
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2021 - 02/2001
3	Body Weight (Weight, Body) 03/2021 - 01/2016
3	Parkinson Disease (Parkinson's Disease) 01/2020 - 09/2001
3	Colonic Neoplasms (Colon Cancer) 03/2017 - 10/2004
3	Stomach Neoplasms (Stomach Cancer) 05/2006 - 12/2000
2	Proteinuria 03/2024 - 09/2020
2	Overweight 01/2024 - 03/2021
2	Lung Injury 04/2023 - 09/2009
2	Fibrosis (Cirrhosis) 10/2022 - 10/2021
2	Pathologic Constriction (Stenosis) 10/2022 - 10/2018
2	Lung Neoplasms (Lung Cancer) 07/2021 - 06/2012
2	Fatty Liver 03/2021 - 06/2018
2	Nervous System Diseases (Neurological Disorders) 09/2018 - 06/2006
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 05/2018 - 01/2012
2	Hyperthermia 03/2018 - 01/2018
2	Hereditary Nephritis (Alport Syndrome) 10/2017 - 09/2016
2	Nephrotic Syndrome (Syndrome, Nephrotic) 10/2017 - 10/2017
2	Hypoxia (Hypoxemia) 08/2016 - 09/2001
2	Colitis 03/2015 - 01/2012
2	Melanoma (Melanoma, Malignant) 06/2014 - 02/2010
2	Crohn Disease (Crohn's Disease) 01/2012 - 07/2010
2	Rheumatoid Arthritis 01/2012 - 01/2008
2	Stroke (Strokes) 09/2010 - 08/2006
2	Ischemic Stroke 09/2010 - 08/2009
2	Pancreatic Neoplasms (Pancreatic Cancer) 10/2004 - 12/2001
2	Sleep Deprivation 01/2003 - 11/2000
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 02/2002 - 05/2001
2	Heart Failure 12/2001 - 07/2000
2	Narcolepsy 01/2001 - 11/2000
2	Sleep Wake Disorders 01/2001 - 11/2000

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 04/2023 - 08/2000
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2024 - 06/2001
7	Messenger RNA (mRNA)IBA 04/2023 - 08/2000
5	Biomarkers (Surrogate Marker)IBA 01/2024 - 11/2007
5	DNA (Deoxyribonucleic Acid)IBA 10/2012 - 07/2001
5	AntigensIBA 01/2011 - 08/2001
4	LigandsIBA 03/2023 - 09/2000
4	Long Noncoding RNAIBA 07/2021 - 01/2017
4	LipidsIBA 04/2021 - 05/2001
4	Retinaldehyde (Retinal)IBA 09/2020 - 08/2008
4	RNA (Ribonucleic Acid)IBA 01/2020 - 12/2001
4	CytokinesIBA 09/2009 - 09/2001
3	AlbuminsIBA 06/2023 - 12/2001
3	Blood Glucose (Blood Sugar)IBA 10/2021 - 11/2010
3	MicroRNAs (MicroRNA)IBA 05/2021 - 04/2010
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2003
3	Transcription Factors (Transcription Factor)IBA 10/2020 - 08/2016
3	Lysine (L-Lysine)FDA Link 01/2020 - 08/2013
3	salvicineIBA 09/2001 - 01/2001
2	Interleukin-6 (Interleukin 6)IBA 03/2024 - 09/2001
2	Therapeutic UsesIBA 03/2024 - 01/2008
2	Apolipoproteins E (ApoE)IBA 01/2024 - 01/2023
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 04/2023 - 06/2001
2	CreatinineIBA 10/2021 - 09/2020
2	Phosphoglycerate Mutase (Phosphoglyceromutase)IBA 03/2020 - 01/2017
2	Phosphates (Orthophosphate)IBA 12/2019 - 01/2018
2	Toll-Like Receptors (Toll-Like Receptor)IBA 06/2019 - 09/2010
2	Uric Acid (Urate)IBA 06/2018 - 07/2017
2	Hemoglobins (Hemoglobin)IBA 10/2017 - 02/2002
2	EnzymesIBA 01/2017 - 12/2000
2	VaccinesIBA 12/2016 - 05/2006
2	Hormones (Hormone)IBA 09/2016 - 09/2001
2	Estrogens (Estrogen)FDA Link 01/2016 - 09/2001
2	Peptides (Polypeptides)IBA 11/2015 - 09/2001
2	AntibodiesIBA 10/2012 - 10/2000
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 04/2010 - 02/2009
2	Interleukin-1beta (Interleukin 1 beta)IBA 09/2009 - 04/2009
2	Complementary DNA (cDNA)IBA 11/2006 - 01/2003
2	Cadherins (E-Cadherin)IBA 02/2006 - 10/2001
2	FibrinIBA 09/2004 - 04/2000
2	Surface-Active Agents (Surfactants)IBA 02/2002 - 05/2001
2	Insulin (Novolin)FDA Link 09/2001 - 09/2000
2	NeuropeptidesIBA 09/2001 - 01/2001
2	OrexinsIBA 01/2001 - 11/2000

Therapy/Procedure

14	Therapeutics 10/2023 - 12/2001
5	Drug Therapy (Chemotherapy) 07/2021 - 02/2001
5	Transplantation 11/2015 - 10/2001
2	Liver Transplantation 10/2022 - 12/2014
2	Sutures (Suture) 09/2022 - 12/2017
2	Cesarean Section (Caesarean Section) 06/2021 - 11/2015
2	Lymph Node Excision (Lymph Node Dissection) 12/2017 - 11/2015
2	Aftercare (After-Treatment) 10/2017 - 07/2002
2	Contraindications 06/2011 - 09/2009